In a time characterized by digital transformation – the healthcare industry has undergone a significant change due to the incorporation of innovative medical software solutions. In 2025, the worldwide healthcare software industry is flourishing, driven by rising demand for electronic health records’, telehealth, data analysis and patient interaction platforms. Amidst numerous companies driving this digital health transformation, several distinguish themselves through their scale, innovation and influence.
Here is an in-depth examination of the 10 biggest and most impactful medical software firms in 2025, each significantly contributing to the evolution of healthcare
- Epic systems corporation
Headquarters: Verona, Wisconsin, USA
Specialization: electronic health records (EHR), management of revenue cycle, engagement of patients
Epic remains a leader in the worldwide healthcare IT sector with its strong suite of electronic health records (EHR) Offerings. Some of the biggest hospital systems in the world rely on Epic because it offers completely integrated software that covers clinical, operational, and financial procedures. The company is a great option for healthcare institutions seeking a unified digital infrastructure because of its interoperability capabilities and patient centered design. Emphasizing scalability and AI integration – epic upholds its standing as a frontrunner in all-encompassing healthcare software
- Cerner corporation (An Oracle company)
Headquarters: Kansas City, Missouri, USA
Specialisation: cloud based EHR, Management of health population, Data analytics.
After being acquired by Oracle – Cerner has greatly enhanced its capabilities by utilising Oracle’s cloud infrastructure. Cerner remains a leading EHR provider and now provides even more sophisticated tools’ for managing population health, analyzing big data and delivering virtual care. Its solution aim to boost clinical efficiency, lessen administrative load, and enhance patient results, establishing it as a key component in the healthcare digital ecosystem
- Athenahealth
Headquarters: Watertown, massachusetts, USA
Specialisation: cloud centric practice administration, revenue cycle services, Telehealth
Athenahealth is notable for its groundbreaking cloud-based system that assists healthcare providers in handling administrative and financial tasks. Athenahealth – which is well known for its user-friendly interface and real time information provides solutions’ that simplify patient interaction, scheduling, invoicing, and other processes. By 2025, its improved data sharing abilities and telehealth functionalities have cemented its position as one of the world’s leading healthcare software providers
- Oracle health
Headquarter: Austin, Texas, USA
Specialisation: entrepreneur software, cloud based EHR, AI incorporation
Oracle’s increased involvement in healthcare through the Cerner acquisition and the creation of its own health technology solutions has established it as a significant player in the sector. Its software offers robust cloud based infrastructure, cybersecurity capabilities and real time analytics to support healthcare plans, hospitals, and research institutes. Oracle Health’s focus on standardization and interoperability is transforming data movement throughout care networks
- ScienceSoft
Headquarters: Mckinney, Texas, USA
Specialization: Tailored healthcare software development, EHR, Telemedicine, consulting
ScienceSoft is a reliable technology ally for healthcare institutions in need of custom software development. The firm provides comprehensive healthcare IT services, like telehealth systems, mobile health application, medical imaging management and HIPAA-compliant software development. Recognized for its technical proficiency and specialized knowledge in the industry – ScienceSoft is particularly appreciated for providing customised solutions that address the changing requirements of healthcare providers
- GE healthcare
Headquarters: Chicago, Illinois, USA
Specialization: Imaging software, clinical workflow solutions, digital diagnostics.
One of the leading manufacturers of medical devices – GE healthcare, also offers extensive digital healthcare systems. Their software for medical imaging and Diagnostic powered by data improves clinical decision making in clinics and hospitals. In 2025, GE has established itself as one of the biggest providers of medical software, especially in the field of diagnostic and imaging technology, through its AI driven radiology and patient monitoring platforms
- eClinicalWorks
Headquarters: Westborough, Massachusetts, USA
Specialisation: EHR, population health, and patient relationship management
Because of its affordable and adaptable EHR solution, eClinicalWorks has expanded quickly, particularly for small and mid-sized offices. Its cloud based software is praised for its user friendliness, comprehensive patient data insights, and smooth telehealth integration. The company’s focus on real time analytics, chronic care management, remote patient monitoring has positioned it as an essential participant in the healthcare software landscape
- Babylon health
Headquarters: London, United Kingdom
Specialisation: Telehealth enabled by AI, digital diagnostics, online consultations
Babylon health persists in transforming the healthcare experience with its AI powered telemedicine platforms. Centred on enhancing healthcare availability especially in neglected areas – Babylon provides primary care services and symptom assessment tools through a digital first approach. By merging AI with immediate consultations and digital records, Babylon symbolises the future of individualised and accessible healthcare
- Northgate public services (A division of NEC)
Headquarters: Hemel Hempstead, United Kingdom
Specialization: Health IT in the public sector, analytics for population health, government health services.
Northgate public services focuses on software solutions for public health systems maintaining a solid presence in the UK and other Commonwealth countries. The firm provides instruments for patient management, healthcare analysis, and health data exchange, particularly in publicly operated organisations. Their proficiency is handling expensive data and assisting national health initiatives renders’ them an essential ally in the digital transformation of public sector healthcare
- Brainhub
Headquarters: Gliwice, Poland
Specialization: Tailored health software, mobile health apps, cross platform solutions.
Brainhub is a specialized software development company that specializes in healthcare innovation. Hospitals and health startups can quickly implement scalable, user friendly applications for patients and professionals through their flexible development methodology. In 2025, brainhub persists in receiving acclaim for its efforts on patient portals, mobile Diagnostic, and digital health monitoring applications
The healthcare sector is no longer characterised exclusively by Doctors, hospitals, or insurers – it is more and more influenced by software. These ten biggest medical software firms’ of 2025 have shown how digital tools may enhance patient care, lessen administrative workloads and spur systemic innovation. Through extensive EHR systems, AI driven Diagnostic or tailored mobile applications, these entities are leading the way in a swiftly changing digital health landscape.
These businesses are not only at the forefront of the healthcare industry, but are also redefining it as a demand for more intelligent, quicker, and safer healthcare solutions globally.
